GeneticsbioRxivPreprint
Long-read transcriptomic identification of synaptic adaptation to amyloid pathology in the App(NL-G-F) knock-in mouse model of the earliest phase of Alzheimer's disease
Ümran Yaman, Gareth T. Banks, Emil Karl Gustavsson…·Dervis A. M. Salih
The paper uses long-read RNA-seq to study splicing changes in an Alzheimer's mouse model, identifying novel transcript isoforms and alternative splicing events in response to amyloid-beta.