Author

Mallory Shin

Stead Family Department of Pediatrics, University of Iowa, Iowa City, IA, USA;

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 1

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Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Diwakar Shukla· 1 shared Elizabeth Phillippi· 1 shared Eric Giavedoni· 1 shared Ganesh V. Pusapati· 1 shared Mark L. Schultz· 1 shared Murugesh PadmanarayanaiD· 1 shared Parijat SarkariD· 1 shared Rajat RohatgiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Diwakar Shukla

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1 paper

Recent·Most cited

Tiled base editing screens uncover rare second-site mutations that rescue a misfolded disease protein

Shivali Rawat, Parijat Sarkar, Eric Giavedoni, Ganesh V. Pusapati, Murugesh Padmanarayana, Mallory Shin, Elizabeth Phillippi, Taylar Simmons, Ruth Azaria, Diwakar Shukla, Mark L. Schultz, Rajat Rohatgi

The paper uses base editing screens to identify second-site mutations that correct misfolded NPC1 proteins, enabling therapeutic applications for diseases like Niemann-Pick type C.

bioRxiv · Nov 2, 2026 · PreprintCell Biology