Automated quantification of white matter hyperintensity confluence: A measure of spatial organisation beyond volume and visual rating scales
Tatjana Schmidt, Robert Salzmann, Marcella Montagnese, Dennis Chan, Jose Bernal, Malte Pfister, Philipp Arndt, Oliver Peters, Julian Hellmann‐Regen, Lukas Preis, Daria Gref, Josef Priller, Eike Jakob Spruth, Maria Gemenetzi, Slawek Altenstein, , Timothy Rittman
This paper introduces an automated method to quantify white matter hyperintensity confluence, showing it correlates with cognitive performance and dementia subtypes beyond volume.
bioRxiv · Jul 28, 2026 · PreprintNeuroscience