Mutation-induced heterogeneity of the β7-β8 loop of the Staphylococcus aureus class A sortase leading to enhanced catalytic efficiency characterized by NMR and enzyme kinetics
Erich G. Walkenhauer, Noah Cox-Tigre, Manish Chaubey, Raphael Marcenac, Adam Wachsman, Hanna M. Kodama, Katy M. Lindblom, Claire E Bloom, John M. Antos, George P. Lisi, Serge L. Smirnov, Jeanine F. Amacher
This paper investigates how mutations in the β7-β8 loop of Staphylococcus aureus sortase affect catalytic efficiency using NMR and enzyme kinetics.
bioRxiv · Aug 24, 2026 · PreprintBiochemistry