Spatial separation provides the force-coupling mechanism for the spindle assembly checkpoint
Chyi Wei Chung, Daniel Grant, Daniel P. Gold, Jack Douglas, Manton Leung, Francis A. Barr, Ulrike Grüneberg
This study shows that spatial separation of Aurora B from the outer kinetochore regulates MPS1 recruitment and SAC signaling during mitosis.
bioRxiv · Sep 25, 2026 · PreprintCell Biology