Author

Manuel A. Alvarez

University of Wisconsin–Madison

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Cell Biology· 1

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Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:protein folding & dynamics· 1

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Claire E. RichardsoniD· 1 shared Nikita Shiliaev· 1 shared Ruiling Zhong· 1 shared Sherlyn Putri Wijaya· 1 shared Sophie Baumberger· 1 shared

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2026-2026 · peak 1/yr

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Claire E. RichardsonORCID

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1 paper

Recent·Most cited

Cell BiologyMolecular Biology of the CellPeer-reviewedMay 20, 2026

Analysis in vivo using a new method, ARGO (Analysis of Red Green Offset), reveals complexity and cell-type specificity in presynaptic turnover of synaptic vesicle protein Synaptogyrin/SNG-1

Nikita Shiliaev, Manuel A. Alvarez, Ruiling Zhong…·Claire E. Richardson

This paper introduces ARGO, a method to quantify protein turnover in vivo, and uses it to show that Synaptogyrin/SNG-1 partitions into two distinct presynaptic pools with different turnover rates in C. elegans neurons.

2 citations

C. elegansfluorescence / live-cell microscopy