Author

Marcell Lederer

Institut of Molecular Medicine, Martin Luther University Halle-Wittenberg, Halle, Germany;

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Organism:Arabidopsis· 1 Organism:C. elegans· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

Alice Wedler-GeyeriD· 2 shared Andrea SinziD· 2 shared Christian H. IhlingiD· 2 shared Stefan HuettelmaieriD· 2 shared Tommy Fuchs· 2 shared Claudia Misiak· 1 shared Dirk Taenzler· 1 shared Frank HauseiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBioinformatics

Alice Wedler-GeyerORCID

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2 papers

Recent·Most cited

Local fractal dimension as an indicator of functional reorganization in molecular interaction networks

Frank Hause, Alice Wedler-Geyer, Marcell Lederer, Tommy Fuchs, Christian H. Ihling, Dirk Taenzler, Rene Keil, Oleksandr Sorokin, Sebastian Wussow, Andrea Sinz, Stefan Huettelmaier

The paper introduces DIFFRACT, a framework that uses local fractal dimension changes in protein interaction networks to detect functional reorganization, showing its utility in identifying novel biological roles in RAVER1-deficient cells.

bioRxiv · Nov 2, 2026 · PreprintBioinformatics

RAVER1 interconnects lethal EMT and miR/RISC activity by the control of alternative splicing

Alice Wedler, Nadine Bley, Markus Glaß, Simon Müller, Laura Schian, Kingsley Benjamin Obika, Marcell Lederer, Claudia Misiak, Tommy Fuchs, Marcel Köhn, Roland Jacob, Tony Gutschner, Christian H. Ihling, Andrea Sinz, Stefan Hüttelmaier

This paper investigates RAVER1's role in controlling alternative splicing and its impact on miR/RISC activity and EMT in cancer cells.

bioRxiv · Jun 14, 2023 · PreprintMolecular Biology