Localis-REX: a general protocol for time-resolved spatiofunctional profiling in live cells and C. elegans
Jinmin Liu, Dalu Chang, Marcus Long, Yimon Aye
Localis-REX identifies locale-specific reactive electrophilic metabolite responsive proteins in C. elegans and cultured cells using light-triggered uncaging and proteomics or functional readouts.
bioRxiv · Oct 22, 2026 · PreprintSystems Biology