Mechanism and cellular actions of the potent AMPK inhibitor BAY-3827
Conchita Fraguas Bringas, Mohd Syed Ahangar, Joyceline Cuenco, Hongling Liu, Alex Bernard Addinsall, Maria Lindahl, Ashley J. Ovens, Mark Anthony Febbraio, Marc Foretz, Olga Göransson, John W. Scott, Elton Zeqiraj, Kei Sakamoto
This paper describes the mechanism and cellular effects of the potent AMPK inhibitor BAY-3827, showing it selectively blocks AMPK-dependent functions.
Science Advances · Aug 22, 2025Peer-reviewedBiochemistry