Polygenic effects on the risk of Alzheimer's disease in the Japanese population
Masataka Kikuchi, Akinori Miyashita, Norikazu Hara, Kensaku Kasuga, Yuko Saito, Shigeo Murayama, Akiyoshi Kakita, Hiroyasu Akatsu, Kouichi Ozaki, Shumpei Niida, Ryozo Kuwano, Takeshi Iwatsubo, Akihiro Nakaya, Takeshi Ikeuchi, the Alzheimer’s Disease Neuroimaging Initiative, , Gary R. Conrad
This paper evaluates the polygenic risk score for Alzheimer's disease in Japanese individuals, showing its utility despite genetic differences from European populations.
Alzheimer s Research & Therapy · Feb 27, 2024Peer-reviewedGenetic & Genomic Medicine