Author

Mark D Brigham

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Feng ZhangiD· 1 shared Jonathan S Gootenberg· 1 shared Julia JoungiD· 1 shared Neville E Sanjana· 1 shared Omar O Abudayyeh· 1 shared Randall J Platt· 1 shared Silvana Konermann· 1 shared

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2017-2017 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Feng ZhangORCID

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1 paper

Recent·Most cited

Protocol: Genome-scale CRISPR-Cas9 Knockout and Transcriptional Activation Screening

Julia Joung, Silvana Konermann, Jonathan S Gootenberg, Omar O Abudayyeh, Randall J Platt, Mark D Brigham, Neville E Sanjana, Feng Zhang

This paper describes a protocol for genome-scale CRISPR-Cas9 knockout and transcriptional activation screening, including library design, validation strategies, and timing estimates.

Nature Protocols · Mar 23, 2017Peer-reviewedMolecular Biology