Author

Mark Klinger

Adaptive Biotechnologies

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Bryan Howie· 2 shared Harlan Robins· 2 shared Matthew T Noakes· 2 shared Brad Greenfield· 1 shared Brian C Zhang· 1 shared Edward Osborne· 1 shared Erin Calfee· 1 shared Hussein Al-Asadi· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

Bryan Howie

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2 papers

Recent·Most cited

TACO: An open, interpretable model for microsecond-scale TCR specificity prediction

Marco Antonio Garcia Noceda, Erin Calfee, Brian C Zhang, Edward Osborne, Brad Greenfield, Mark Klinger, Matthew T Noakes, Bryan Howie, Harlan Robins

TACO predicts TCR specificity against HLA-A*02:01-presented peptides using a statistical model, achieving AUROC 0.67 on held-out data and enabling efficient computational evaluation of TCR-peptide interactions.

bioRxiv · Nov 6, 2026 · PreprintImmunology

HLAResolver: A statistical framework for resolving HLA ambiguity in T-cell response data

Hussein Al-Asadi, Matthew T Noakes, Mark Klinger, Bryan Howie, Harlan Robins

HLAResolver improves HLA resolution in T-cell response data by integrating MIRA responses with NetMHCpan predictions, achieving higher sensitivity and fewer candidate HLAs.

bioRxiv · Nov 3, 2026 · PreprintImmunology