Single-cell profiling of environmental enteropathy reveals signatures of epithelial remodeling and immune activation in severe disease
Conner Kummerlowe, Thomas E. Wallach, Simutanyi Mwakamui, Travis K. Hughes, Nolawit Mulugeta, Victor C. Mudenda, Ellen C. Besa, Kanekwa Zyambo, Ira Fleming, Marko Vukovic, Benjamin A. Doran, Toby P. Aicher, Marc H. Wadsworth, Juliet Tongue Bramante, Amiko M. Uchida, , Paul M. Kelly
The paper uses single-cell RNA-sequencing to study environmental enteropathy, identifying epithelial and immune correlates of disease severity and suggesting new therapeutic targets.
bioRxiv · Apr 11, 2021 · PreprintGenomics