Author

Markus Braun

Graz University of TechnologyPrimary ORCID profile (0000-0002-7891-6954 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Markus BrauniD1 paper · Goethe University Frankfurt

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Approach:diffusion model· 1 Research Focus:protein design· 1 Assay:protein structure· 1

Frequent Co-Authors

Adrian TrippiD· 1 shared Aleksandar BijeliciD· 1 shared C. FischeriD· 1 shared David B. StolliD· 1 shared Federico RossiiD· 1 shared Gustav OberdorferiD· 1 shared Horst LechneriD· 1 shared Massimo G. TotaroiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Adrian TrippORCID

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1 paper

Recent·Most cited

Computational enzyme design by catalytic motif scaffolding

Markus Braun, Adrian Tripp, Morakot Chakatok, Sigrid Kaltenbrunner, C. Fischer, David B. Stoll, Aleksandar Bijelic, Wael Elaily, Massimo G. Totaro, Melanie Moser, Shlomo Yakir Hoch, Horst Lechner, Federico Rossi, Matteo Aleotti, Mélanie Hall, Gustav Oberdorfer

This paper introduces Riff-Diff, a machine learning and atomistic modeling method for designing enzymes with high catalytic activity and stereoselectivity, demonstrating its effectiveness for two chemical reactions.

Nature · Dec 3, 2025Peer-reviewedBiochemistry