MAST: A flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA-seq data.
Greg Finak, Andrew McDavid, Masanao Yajima, Jingyuan Deng, Vivian Gersuk, Alex K Shalek, Chloe K Slichter, Hannah W Miller, M Julianna McElrath, Martin Prlic, Peter Linsley, Raphael Gottardo
The paper introduces a statistical framework to analyze single-cell RNA-seq data by modeling bimodality and characterizing transcriptional changes and heterogeneity.
bioRxiv · Jun 15, 2015Bioinformatics