Chemical tools to Detect and Inhibit IgA1 Proteases in Haemophilus influenzae
Vani Verma, Pooja Sabu Thomas, Martina Lancieri, Jasper Van den Bos, Adrian Fabisiak, Sarah Peeters, Marie‐Stéphanie Aschtgen, Edmund Loh, Ingrid De Meester, Hans L. De Winter, Pieter Van der Veken, Michaela Prothiwa
This paper develops chemical tools to detect and inhibit IgA1 proteases in Haemophilus influenzae, identifying novel inhibitors and demonstrating their effectiveness in disrupting immune evasion.
bioRxiv · Mar 18, 2026 · PreprintMicrobiology