Author

Matt Thomson

California Institute of Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:spatial transcriptomics· 2 Research Focus:cell-cell communication· 1 Approach:graph neural network· 1 Approach:statistical model· 1

Frequent Co-Authors

Zitong Jerry WangiD· 2 shared Kevin Fleisher· 1 shared Rex LiuiD· 1 shared Yuning You· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersSystems Biology

Zitong Jerry WangORCID

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2 papers

Recent·Most cited

A spatial representation of information underlies probabilistic computation in cells

Matt Thomson, Zitong Jerry Wang

This paper shows cells use a spatial representation to perform probabilistic source seeking through Bayes filtering, adapting to noise without explicit statistics.

bioRxiv · Feb 12, 2025 · PreprintSystems Biology

Building Foundation Models to Characterize Cellular Interactions via Geometric Self-Supervised Learning on Spatial Genomics

Yuning You, Zitong Jerry Wang, Kevin Fleisher, Rex Liu, Matt Thomson

This paper introduces CI-FM, a foundation model for analyzing cellular interactions in spatial genomics using geometric graph neural networks, achieving high correlation and low error in gene expression inference.

bioRxiv · Jan 25, 2025 · PreprintBioinformatics