Author

Matthew Politz

MRC London Institute of Medical Sciences

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Genomics· 1

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Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:matrix factorization· 1 Assay:scRNA-seq· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Christina ErnstiD· 1 shared Corinna FriedrichiD· 1 shared Elizabeth Ing‐SimmonsiD· 1 shared Frank TüttelmanniD· 1 shared Irina Balaguer BalsellsiD· 1 shared Jahnavi BhaskaraniD· 1 shared Jann‐Frederik CremersiD· 1 shared Juan M. VaquerizasiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Christina ErnstORCID

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1 paper

Recent·Most cited

A single-nucleus multiomic and spatial atlas of gene regulation in human spermatogenesis

Jahnavi Bhaskaran, Elizabeth Ing‐Simmons, Irina Balaguer Balsells, Sara Di Persio, Melanie Chan, Matthew Politz, Jann‐Frederik Cremers, Nadja Rotte, Sabine Kliesch, Corinna Friedrich, Frank Tüttelmann, Christina Ernst, Sandra Laurentino, Nina Neuhaus, Juan M. Vaquerizas

This study creates a single-nucleus multiomic and spatial atlas of human spermatogenesis, linking gene regulatory networks to infertility-associated genetic variation and disease perturbations.

bioRxiv · Sep 8, 2026 · PreprintGenomics