Generation of virtual populations for quantitative systems pharmacology through advanced sampling methods
Miriam Schirru, Tristan Brier, Maxime Petit, Didier Zugaj, Pierre‐Olivier Tremblay, Fahima Nekka
This paper evaluates DREAM(ZS) for generating virtual populations in QSP, showing it outperforms Metropolis-Hastings in parameter space exploration and correlation preservation.
Bulletin of Mathematical Biology · Oct 17, 2025Peer-reviewedSystems Biology