Olive phenolic compounds, potent tankyrase 1 inhibitor exhibit anti colon cancer effects by blocking Wnt/β-catenin pathway
Arindam Sain, Soumen Barman, Dipsikha Khamrai, M. Srinivas, Prerna Singh, Bhargav Simpi, Mayuri Varshney, Debdut Naskar
This study identifies olive polyphenols as tankyrase 1 inhibitors that suppress the Wnt/β-catenin pathway, reducing colon cancer cell viability and target gene expression.
bioRxiv · May 8, 2024 · PreprintCancer Biology