Author

Meagan Ryan

Icahn School of Medicine at Mount Sinai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Aarthi RamakrishnaniD· 1 shared Abner A. Reyes· 1 shared Alex D. Rabinowitz· 1 shared Alison D. Axtman· 1 shared André S. Santiago· 1 shared Ashik GurungiD· 1 shared Benjamin A Garcia· 1 shared Caleb J. BrowneiD· 1 shared

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2018-2024 · peak 1/yr

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10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Aarthi RamakrishnanORCID

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2 papers

Recent·Most cited

Cell-Type-Specific Epigenetic Priming of Gene Expression in Nucleus Accumbens by Cocaine

Philipp Mews, Yentl Y. van der Zee, Hope G. Kronman, Ashik Gurung, Aarthi Ramakrishnan, Caleb J. Browne, Rita Futamura, Molly Estill, Meagan Ryan, Abner A. Reyes, Benjamin A Garcia, Simone Sidoli, Li Shen, Eric J. Nestler

This study identifies a novel epigenetic mechanism by which chronic cocaine exposure alters gene expression in nucleus accumbens neurons through H2A.Z depletion and chromatin changes.

Science Advances · Oct 4, 2024Peer-reviewedMolecular Biology

AAK1 inhibits WNT signaling by promoting clathrin-mediated endocytosis of LRP6

Megan J. Agajanian, Matthew P. Walker, Alison D. Axtman, Roberta R. Ruela-de-Sousa, Alex D. Rabinowitz, David M. Graham, Meagan Ryan, D. Stephen Serafin, James M. Bennett, Rafael M. Couñago, David H. Drewry, Jonathan M. Elkins, Carina Gileadi, Opher Gileadi, Paulo H. Godoi, , Michael B. Major

The paper identifies AAK1 as a negative regulator of WNT signaling through clathrin-mediated endocytosis of LRP6, validated using a new AAK1/BMP2K inhibitor.

bioRxiv · Feb 1, 2018 · PreprintCell Biology