Author

Mengfang Yan

Westlake University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Angelina Li· 1 shared Brian J. LeeiD· 1 shared Chaolin ZhangiD· 1 shared Daniel F. MoakleyiD· 1 shared Fei HouiD· 1 shared Jimin Yoon· 1 shared Jing DuaniD· 1 shared Ke ZhangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Angelina Li

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1 paper

Recent·Most cited

Primate-specific adaptation of Ku protects transcriptomic integrity by suppressing Alu-mediated alternative splicing

Tianji Yu, Jimin Yoon, Yimeng Zhu, Angelina Li, Brian J. Lee, Daniel F. Moakley, Jing Duan, Qiannian Deng, Fei Hou, Mengfang Yan, Vincenzo Alessandro Gennarino, Ke Zhang, Li Chen, Shan Zha, Chaolin Zhang

This study shows that primate-specific Ku adaptation suppresses Alu-mediated alternative splicing, maintaining transcriptomic integrity and linking Ku function to brain development and disease.

bioRxiv · Dec 18, 2025 · PreprintMolecular Biology