Author

Mengxi Yang

Mount Sinai Beth Israel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Approach:experimental assay· 1

Frequent Co-Authors

Aloysius DomingoiD· 2 shared Amanda AllaniD· 2 shared Beomjin JangiD· 2 shared Casey YoungiD· 2 shared Daniele MatteiiD· 2 shared Deborah RaymondiD· 2 shared Kelly AstudilloiD· 2 shared Rachel J. Saunders-PullmaniD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Aloysius DomingoORCID

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2 papers

Recent·Most cited

Peripheral Immune Alterations and T Cell Clonal Dynamics Across the Parkinson's Disease Spectrum

Mikaela R. Rosen, J. Oriol Narcis Majos, Daniele Mattei, Elena Mejia, Carlos Perez Mandry, Beomjin Jang, Kailash BP, Tatsuhiko Naito, Amanda Allan, Tarek Khashan, Charlie Argyrou, Mengxi Yang, Deborah Raymond, Casey Young, Kelly Astudillo, , Towfique Raj

This study uses single-cell RNA sequencing and TCR profiling to analyze immune changes in Parkinson's disease across different stages and identifies sex-dependent immune alterations and TCR diversity.

medRxiv · Sep 29, 2026 · PreprintGenetic & Genomic Medicine

Integrated Stress Response Signatures Drive Monocyte Dysfunction in GBA1- and LRRK2-Linked Parkinson's Disease

Daniele Mattei, Erica Brophy, Mikaela Rosén, Oriol Narcis Majos, Aloysius Domingo, Elena Meijia, Claudia De Sanctis, Beomjin Jang, Tarek Khashan, Mengxi Yang, Deborah Raymond, Casey Young, Jack Humphrey, Elisa Navarro, Amanda Allan, , Towfique Raj

The paper identifies integrated stress response (ISR) signatures and proteostasis defects in monocytes from GBA1- and LRRK2-linked Parkinson's disease, linking them to immune dysfunction.

medRxiv · Oct 8, 2025 · PreprintGenetic & Genomic Medicine