Author

MG Holt

VIB-KU Leuven Center for Brain & Disease Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1

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Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:snRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Alejandro Cisterna‐GarcíaiD· 1 shared Alicia Gómez-PascualiD· 1 shared Andrew KottickiD· 1 shared Araks MartirosyaniD· 1 shared C. A. Altar· 1 shared C. Mameffe· 1 shared Juan Antonio BotíaiD· 1 shared Katja HebestreitiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Alejandro Cisterna‐GarcíaORCID

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1 paper

Recent·Most cited

Single-nucleus co-expression networks of dopaminergic neurons support iron accumulation as a plausible explanation to their vulnerability in Parkinson's disease

Alicia Gómez-Pascual, Araks Martirosyan, Katja Hebestreit, C. Mameffe, Suresh Kumar Poovathingal, T. Grant Belgard, C. A. Altar, Andrew Kottick, MG Holt, Victor J. Hanson-Smith, Alejandro Cisterna‐García, M. Mighdoll, Robert H. Scannevin, Sebastian Guelfi, Juan Antonio Botía

The paper introduces scCoExpNets and CovCoExpNets to analyze cell-type specific gene co-expression networks from single-cell RNA-seq data, identifying iron accumulation as a factor in dopaminergic neuron vulnerability in Parkinson's disease.

bioRxiv · Dec 13, 2022 · PreprintBioinformatics