Atlas-Guided Cell-Specific Transcriptomics Identifies Pathway-Level Remodeling of Human Hypothalamic CRH Neurons in Opioid Use Disorder
Lorna Barrall, Phillip John Urbanczyk, Bruno Kluwe-Schiavon, Laura Stertz, Sakuni Rankothgedera, Micah Castillo, Preethi H. Gunaratne, Consuelo Walss‐Bass
The paper identifies pathway-level remodeling in human hypothalamic CRH neurons in opioid use disorder using single-nucleus RNA sequencing and atlas-guided analysis.
bioRxiv · Sep 21, 2026 · PreprintGenomics