Strategies of mechanical adaptations of circulating tumor cells and properties of their cellular microenvironment have predictive and prognostic biomarker value
Maria Gaczynska, Fatemeh Ataei, Chih-Wei Chou, Matthew A Click, Furkan Dursun, Chia-Nung Hung, Kerri A Kendrick, Robin Leach, Michael A Liss, Penny Vroman, Zhao Zhang, Tim Hui-Ming Huang, Pawel A Osmulski
The paper identifies mechanical adaptations of circulating tumor cells (CTCs) and their microenvironment properties as predictive biomarkers for prostate cancer outcomes.
bioRxiv · Nov 2, 2026 · PreprintCancer Biology