Author

Michael B Doud

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Organism:human· 2 Assay:proteomics· 2 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:phylogenetics / evolution· 1 Research Focus:variant effect prediction· 1 Organism:virus· 1

Frequent Co-Authors

Jesse Bloom· 2 shared Orr Ashenberg· 2 shared Jai Padmakumar· 1 shared Jesse D Bloom· 1 shared

Activity by Year

2015-2016 · peak 2/yr

Co-Author Collaboration Network

4 top collaborators · 3 mutual co-author links

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2 shared papersMicrobiology

Jesse Bloom

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Deep mutational scanning identifies sites in influenza nucleoprotein that affect viral inhibition by MxA

Orr Ashenberg, Jai Padmakumar, Michael B Doud, Jesse Bloom

This study uses deep mutational scanning to identify influenza nucleoprotein sites affecting MxA sensitivity, revealing conserved regions critical for MxA resistance.

bioRxiv · Aug 28, 2016Microbiology

Accurate measurement of the effects of all amino-acid mutations to influenza hemagglutinin

Michael B Doud, Jesse D Bloom

The paper improves the accuracy of measuring amino-acid mutation effects on influenza hemagglutinin by using a helper virus, revealing mutation tolerance in antigenic sites and limited evolution capacity in stalk epitopes.

bioRxiv · Apr 7, 2016Microbiology

Site-specific amino-acid preferences are mostly conserved in two closely related protein homologs

Michael B Doud, Orr Ashenberg, Jesse Bloom

The paper measures amino-acid preferences in two closely related influenza nucleoprotein homologs and shows that site-specific preferences are mostly conserved, improving evolutionary models.

bioRxiv · Jul 16, 2015Evolutionary Biology