Expanding the Repertoire of Photoswitchable Unnatural Amino Acids for Enzyme Engineering
Caroline Hiefinger, Michela Marcon, Verena Pape, Guillem Casadevall, Ranit Lahmy, Christoph Haag, Julian Nazet, Michael Bartl, Astrid Bruckmann, Sílvia Osuna, Burkhard König, Andrea Hupfeld
This study designs and synthesizes six new photoswitchable unnatural amino acids (psUAAs) for enzyme engineering, showing enhanced interaction potential and diverse photochemical behaviors.
Angewandte Chemie International Edition · Aug 4, 2025Peer-reviewedSynthetic Biology