Bayesian copy number detection and association in large-scale studies
Stephen Cristiano, David M. McKean, Jacob Carey, Paige M. Bracci, Paul Brennan, Michael Chou, Mengmeng Du, Steve Gallinger, Michael Goggins, Manal M. Hassan, Rayjean J. Hung, Robert C. Kurtz, Donghui Li, Lingeng Lu, Rachel Ε. Neale, , Robert B. Scharpf
This paper develops a Bayesian method to detect copy number variants and assess their association with disease in large-scale studies, finding deletions near MYC and TUSC3 linked to pancreatic cancer.
BMC Cancer · Sep 7, 2020Peer-reviewedGenetics