Single nuclear RNA sequencing shows altered microglial and astrocytic functions in post-mortem Parkinson's disease tissue
Indra Roy, Michael Fiorini, Rhalena A. Thomas, Georgina Jiménez Ambriz, Sali M.K. Farhan, Valerio E. C. Piscopo, Thomas M. Durcan
This study uses snRNA-seq data from post-mortem Parkinson's disease tissue to identify altered molecular pathways in microglia and astrocytes, showing upregulated protein misfolding responses and downregulated inflammation-related genes.
BMC Genomic Data · Jul 4, 2026Peer-reviewedNeuroscience