Molecular cascades and cell-type specific signatures in ASD revealed by single cell genomics
Brie Wamsley, Lucy K. Bicks, Yuyan Cheng, Riki Kawaguchi, Diana Quintero, Jennifer Grundman, Jianyin Liu, Shaohua Xiao, Natalie Hawken, Michael Margolis, Samantha Mazariegos, Daniel H. Geschwind
The paper uses single nuclear RNAseq and epigenetic profiling to identify molecular changes and cell-type specific signatures in ASD, linking them to genetic risk factors.
Science · May 23, 2024Peer-reviewedNeuroscience