Stable heteroplasmy at the single cell level is facilitated by inter-cellular exchange of mtDNA
Anitha D Jayaprakash, Erica Benson, Swapna Gone, Raymond Liang, Jaehee Shim, Luca Lambertini, Masoud M Toloue, Mike Wigler, Stuart Aaronson, Ravi Sachidanandam
The paper demonstrates stable heteroplasmy in single cells through inter-cellular mtDNA exchange and introduces Mseek for sensitive mtDNA analysis.
Nucleic Acids Research · Feb 4, 2015Peer-reviewedGenetics