Author

Mindolay Fike

University of Virginia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1

Frequent Co-Authors

Gabrielle Martinez· 1 shared Kristen M. NaegleiD· 1 shared Madhuri Sosale· 1 shared Swathi ShekharaniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperMolecular Biology

Gabrielle Martinez

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1 paper

Recent·Most cited

Studying the effect of conserved tyrosine phosphorylation within SH2 domains

Gabrielle Martinez, Mindolay Fike, Madhuri Sosale, Swathi Shekharan, Kristen M. Naegle

This study investigates how phosphorylation at specific tyrosine sites within SH2 domains affects ligand binding, finding that phosphorylation at Y63 in PTPN11 reduces binding of physiologically relevant substrates.

bioRxiv · Aug 18, 2026 · PreprintMolecular Biology