Assessing the measurement transfer function of single-cell RNA sequencing
Hannah R. Dueck, Rizi Ai, Adrian Camarena, Bo Ding, Reymundo Dominguez, Oleg V. Evgrafov, Jian-Bing Fan, Stephen A. Fisher, Jennifer S. Hernstein, Tae Kyung Kim, Jae Mun (Hugo) Kim, Ming-Yi Lin, Rui Liu, William J. Mack, Sean McGroty, , Junhyoung Kim
This study evaluates the performance of three scRNA-seq methods through controlled experiments, finding they reliably detect genes above 5-10 molecules with linear measurement transfer functions.
bioRxiv · Mar 24, 2016 · PreprintGenomics