A new class of penicillin-binding protein inhibitors to address drug-resistant Neisseria gonorrhoeae
Tsuyoshi Uehara, Allison L. Zulli, Brittany Miller, Lindsay M. Avery, Steven A. Boyd, Cassandra L. Chatwin, Guo‐Hua Chu, Anthony S. Drager, Mitchell Edwards, Susan G. Emeigh Hart, Nathan J. Line, Cullen L. Myers, Gopinath Rongala, Annie Stevenson, Kyoko Uehara, , Stephen M. Condon
This paper identifies a novel benzoxaborinine-based inhibitor (VNRX-14079) that effectively targets penA-mediated resistance in multidrug-resistant Neisseria gonorrhoeae.
Nature Microbiology · Apr 8, 2026Peer-reviewedMicrobiology