Author

Mohammad Dehestani

German Center for Neurodegenerative Diseases

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 2 Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Thomas GasseriD· 4 shared Vikas BansaliD· 3 shared Ernest FraenkeliD· 2 shared Nasser Karmali· 2 shared Wenhua Sun· 2 shared Alice BrauniD· 1 shared Ashutosh DhingraiD· 1 shared Benjamin RöebeniD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersNeuroscience

Thomas GasserORCID

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Author profile →

4 papers

Recent·Most cited

Single-cell transcriptomic changes in oligodendroglial lineage cells derived from Parkinson's disease patient-iPSCs with LRRK2-G2019S mutation

Nasser Karmali, Wiebke Kessler, Mohammad Dehestani, Wenhua Sun, Layla Drwesh, Polina Volos, Stanislav Tsitkov, Ashutosh Dhingra, Christian Thomas, Salvador Rodrı́guez-Nieto, Julia Tietz, David Schafflick, Noémia Fernandes, Julia Fitzgerald, Ernest Fraenkel, , Vikas Bansal

The paper investigates transcriptomic changes in oligodendroglial lineage cells from PD patient-iPSCs with LRRK2-G2019S mutation, identifying altered pathways and signaling in OPCs and ODCs.

iScience · Jun 19, 2026Peer-reviewedNeuroscience

Unraveling the Genetic Overlap Between Parkinson's Disease and Schizophrenia Through Genome-wide Association and Cell-Type Specific Transcriptomic Analysis

Wenhua Sun, Mohammad Dehestani, Alice Braun, Nasser Karmali, Isabel Wurster, Benjamin Röeben, Roswitha Kemmner, Kathrin Brockmann, Manu Sharma, Marina Mitjans, Fabian Streit, Thomas Gasser, Vikas Bansal

This study identifies shared genetic loci between Parkinson's disease and schizophrenia using GWAS and scRNA-seq, highlighting RAI1's role in mitochondrial dysfunction and non-motor symptoms.

medRxiv · Jun 16, 2026 · PreprintGenetic & Genomic Medicine

Transcriptomic changes in oligodendrocytes and precursor cells predicts clinical outcomes of Parkinsons disease

Mohammad Dehestani, Velina Kozareva, Cornelis Blauwendraat, Ernest Fraenkel, Thomas Gasser, Vikas Bansal

The paper identifies transcriptomic changes in oligodendrocytes and precursor cells linked to Parkinson's disease outcomes and shows their predictive value for cognitive and depressive symptoms.

Molecular Brain · Aug 13, 2024Peer-reviewedNeuroscience

Assessment of SLC25A46 variants in Parkinson's disease

Hui Liu, Mohammad Dehestani, Mary B. Makarious, Sara Bandrés‐Ciga, Thomas Gasser, Jonggeol Jeffrey Kim

The paper investigates SLC25A46 variants in Parkinson's disease using whole-genome sequencing data and finds no significant association with PD in European ancestry populations.

medRxiv · Jun 13, 2022 · PreprintGenetic & Genomic Medicine