MicroRNA-directed control of complex mRNA stability patterns across cell types
Lukas Oesinghaus, Sebastian M. Castillo-Hair, Morgan Bean, Nicole Ludwig, Shusruto Rishik, Hao Yuan Kueh, Andreas Keller, Georg Seelig
The paper develops a model to predict mRNA stability based on microRNA expression data and applies it to design microRNA-responsive constructs with specific activity patterns across cell types.
bioRxiv · Oct 28, 2024 · PreprintSynthetic Biology