Convergent Evolution and B-Cell Recirculation in Germinal Centers in a Human Lymph Node
A. Pelissier, M. Stratigopoulou, N. Donner, E. Dimitriadis, R. J. Bende, J. E. Guikema, M. R. Martinez, C. J. M. van Noesel
The paper analyzes B-cell clonal diversity and evolution in human germinal centers using LCM and Rep-seq, finding convergent evolution and shared antigen responses across GCs.
bioRxiv · Nov 9, 2022Evolutionary Biology