Transcriptional changes consistent with altered neuronal differentiation, angiogenesis, and tumor plasticity induced in human subpallial telencephalic organoid-glioblastoma chimeras.
S. Chiola, J. Yang, H. M. A. Ullah, K. Napan, Q. Huang, N. Gamboa, O. Youssef, H. Colman, S. Cheshier, A. Shcheglovitov
This study investigates reciprocal interactions between human subpallial telencephalic organoids and GBM spheroids, identifying transcriptional changes linked to neuronal differentiation, angiogenesis, and tumor plasticity.
bioRxiv · May 11, 2023 · PreprintCancer Biology