Redox-dependent condensation and cytoplasmic granulation by human ssDNA binding protein 1 delineate roles in oxidative stress response
G. M. Harami, J. Palinkas, Z. J. Kovacs, B. Jezso, K. Tarnok, H. Harami-Papp, J. Hegedüs, L. Mahmudova, N. Kucsma, S. Toth, G. Szakacs, M. Kovacs
This study shows hSSB1 undergoes redox-dependent LLPS to form cytoplasmic granules involved in oxidative stress response and genome repair.
bioRxiv · Jul 25, 2023Biochemistry