Cancer BiologybioRxiv
Cancer stem cell-derived extracellular vesicles preferentially target MHCII- macrophages and PD1+ T cells in the tumor microenvironment
P. Gonzalez-Callejo, Z. Guo, T. Ziglari…·F. Pucci
The paper identifies CSC-derived extracellular vesicles that target MHCII- macrophages and PD1+ T cells, suggesting combination therapies targeting these cells may reduce HNSCC recurrence.
DOI 10.1371/journal.pone.0279400