Diffusion Probabilistic Models for Missing-Wedge Correction in Cryo-Electron Tomography
Nadeer Hasan, Aurélie Bertin, Slavica Jonić
The paper introduces MW-RaMViD, a diffusion model for correcting missing-wedge artifacts in cryo-ET by generating missing tilt images, showing improved reconstruction fidelity with smaller step sizes and larger conditioning windows.
bioRxiv · Feb 17, 2026 · PreprintBioinformatics