A Novel Natural Killer Cell Expansion Technology for the Development of Cellular Immunotherapies
Ammelie Svea Boje, Anna Langner, Alexander Jochimsen, Carina Lynn Gehlert, Steffen Krohn, Dorothee Winterberg, Sonja Bendig, Eva Maria Murga Penas, Guranda Chitadze, Monika Brüggemann, Lars R. Fransecky, Katharina Diemer, Dirk Bauerschlag, Natalie Baum, Daniela Wesch, , Matthias Peipp
This paper introduces a multifunctional fusion protein that enables efficient ex vivo expansion of NK cells from various sources and enhances their cytotoxic activity against tumor cells.
bioRxiv · Jan 22, 2026 · PreprintImmunology