Author

Nicholas Leschinsky

Rush University Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander CicalaiD· 1 shared Alicia GibbonsiD· 1 shared Andrei V. KarginoviD· 1 shared Athanasios PapadasiD· 1 shared Courtney ColemaniD· 1 shared Daniel J. Lagal· 1 shared Duncan Hong· 1 shared Dustin A. DemingiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

Alexander CicalaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A matrikine organizes the dendritic cell- T cell triads that build tertiary lymphoid structures

Daniel J. Lagal, Duncan Hong, Athanasios Papadas, George Yacu, Emma Geatches, Nicholas Leschinsky, Yun Huang, Yaling Dou, Matteo Fields, Alicia Gibbons, Elsa Molina, Kersi N. Pestonjamasp, Péter T. Tóth, Alexander Cicala, João I. Mamede, , Fotis A. Asimakopoulos

This study identifies versikine, a matrikine derived from VCAN proteolysis, as essential for organizing dendritic cell-T cell triads in tertiary lymphoid structures and enhancing antitumor immunity.

bioRxiv · Oct 29, 2026 · PreprintImmunology

Tuning a light-regulated allosteric switch for enhanced temporal control of protein activity

Jacob Matsche, Jordan Fauser, Trisha Bansal, Nicholas Leschinsky, Courtney Coleman, Andrei V. Karginov

This paper enhances an optogenetic tool called LightR by modifying its VVD domains and linker to create variants with improved dynamic range and faster activation kinetics for better control of protein activity.

bioRxiv · Apr 2, 2026 · PreprintSynthetic Biology