Explainable models using transcription factor binding and epigenome patterns at promoters reveal disease-associated genes and their regulators in the context of cell-types
Omkar Chandra, Durjay Pramanik, Srishti Gautam, Madhu Sharma, Niharika Dubey, Biswarup Mahato, Yuriy Lvovich Orlov, Vibhor Kumar
The paper uses epigenetic features to predict disease-associated genes and their regulators, emphasizing cell-type context and validating findings with genomic data.
bioRxiv · May 6, 2024 · PreprintBioinformatics