Nuclear Speckles are Regulatory Hubs for Viral and Host mRNA Expression During HSV-1 Infection
Shani Nadav-Eliyahu, Chaya Bohrer, Alon Boocholez, Noa Kinor, Vesa Aho, Jennifer I. C. Benichou, Salla Mattola, Sami Salminen, Henri Niskanen, Minna Unelma Kaikkonen, Maija Vihinen‐Ranta, Yaron Shav‐Tal
This paper shows that nuclear speckles regulate viral and host mRNA processing and export during HSV-1 infection, with viral transcripts uniquely relying on speckles for export.
Proceedings of the National Academy of Sciences · Feb 2, 2026Peer-reviewedCell Biology