Transient kinetic analysis of SWR1C-catalyzed H2A.Z deposition unravels the impact of nucleosome dynamics and the asymmetry of stepwise histone exchange
R. K. Singh, S. Watanabe, O. Bilsel, C. L. Peterson
This study uses transient kinetic analysis to reveal how SWR1C catalyzes H2A.Z deposition, showing asymmetry in ATP-dependent dimer exchange and nucleosome dynamics.
bioRxiv · Apr 19, 2018Biochemistry