Discovery of 1,3,4-oxadiazoles with slow-action activity against Plasmodium falciparum malaria parasites
K. T. Andrews, G. M. Fisher, M. Firmin, A. Liepa, T. Wilson, J. Gardiner, Y. Mohri, A. Rai, A. K. Davey, A. Masurier, A. Delion, A. A. Mouratidis, O. Hutt, J. N. Burrows, J. H. Ryan, , T. S. Skinner-Adams
The paper identifies new antiplasmodial compounds with slow-action activity but highlights pharmacokinetic limitations for in vivo efficacy.
bioRxiv · Mar 9, 2023 · PreprintMicrobiology