An Observational Study of the Impact of Systemic B-cell Depletion on Cervicovaginal Mucosal Environment
Ofri Bar, Meena Murthy, Katherine M. Cosgrove, Yusra Saidi, Wafae El-Arar, Miles Goldenberg, Gabriel Sauvage, Agnès Bergerat, Briah Cooley Demidkina, Karen A. Laliberte, Jiawu Xu, Grace Pierson, Douglas S. Kwon, John L. Niles, Moran Yassour, Caroline M. Mitchell
This study examines how rituximab treatment affects vaginal mucosal immune markers, immune cell populations, and microbiome composition in women compared to healthy controls.
bioRxiv · Apr 21, 2026 · PreprintImmunology