The effect of pH alterations on TDP-43 in a cellular model of amyotrophic lateral sclerosis
Y. Al Ojaimi, C. Slek, S. Osman, H. Alarcan, S. Marouillat, P. Corcia, P. Vourc'h, D. Lanznaster, H. Blasco
This study investigates how pH changes affect TDP-43 localization and aggregation in a cellular model of ALS, finding increased cytoplasmic puncta at extreme pH levels.
bioRxiv · Dec 21, 2022Cell Biology